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Shingles vaccine linked to lower risk of heart attack and stroke

scienceAug 26, 2026221,087

A study led by Dr Maxime Taquet at the University of Oxford found that the two-dose shingles vaccine Shingrix was associated with a 12% lower risk of cardiovascular diagnoses, including heart attack, heart failure and stroke, in the first three and a half years after vaccination among 70,000 US adults aged 60 and over. The researchers used a natural experiment around the rapid US switch from Zostavax to Shingrix in 2017 to compare vaccinated people before and after the change, then tracked records for seven years after vaccination. By the end of follow-up the vaccine was associated with a 4% lower risk of cardiovascular disease. Taquet said the effect, if confirmed in randomized trials, could be equivalent to taking daily blood pressure lowering medication and might prevent hundreds of thousands of coronary heart disease, stroke and heart failure cases worldwide. The team published the study in Nature Medicine and noted several trials are already under way to provide more definitive evidence. Investigators are exploring why Shingrix might protect the heart and brain, including prevention of shingles-related cardiovascular risk and broader vaccine-driven reductions in inflammatory proteins.

Alex von Tunzelmann
@alexvont.bsky.social

There’s already research connecting the Shingrix vaccine to a significantly reduced risk of dementia. Now it looks like it might also significantly reduce risks of heart attacks and strokes. NHS it at 65 in the UK but you can pay privately & get it from age 50 www.theguardian.com/science/2026...

2352h ago
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