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Christina Applegate says she was misdiagnosed with multiple sclerosis

tvOct 20, 20262726

Christina Applegate told listeners on her MeSsy podcast Tuesday that doctors misdiagnosed her with multiple sclerosis after new testing showed she does not have MS. Applegate returned to the show after a seven-month break and tearfully said the discovery came from new technology and left her "back at square one." She described the revelation as shocking and profanity-laced and said she still does not know what is causing her symptoms. Applegate has publicly discussed her health struggles previously and framed the misdiagnosis as a profound setback; she said the outcome wiped away the explanation she had been living with. The announcement resets her search for answers and for what comes next in her care and treatment.

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